39 次染色質開放性測序(ATAC-seq)原理以及應用領域 2025-4-30
技術簡介染色質開放性測序(Assay for Transposase-Accessible Chromatin using sequencing,ATAC-seq),一種用于檢測染色質開放性的高通量測序技術,通過Tn5轉座酶切割并標記開放的染色質區域
56 次ATAC-seq開啟新視角:探索Shox2基因沙漠的神秘功能 2025-4-30
2024年7月,發表在《Nature Communications》的一篇文章“A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival”,聚焦Shox2基因
182 次機械拉伸誘導的活性氧驅動新生豬腎上皮細胞內皮素的產生 2025-4-27
Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cellsKeywords: Acute kidney injury; Endothelin; Endothelin
214 次Hes1/Piezo1 通路在糖皮質激素誘導的骨質疏松癥中的關鍵作用 2025-4-22
The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosisKeywords: Bone biology; Bone disease; Osteoporosis; Therapeutics.糖皮質激素
329 次DAP-seq技術助力揭示擬南芥根基本組織發育的調控機制 2025-4-21
2024 年 11月 18 日,蘭州大學黎家教授團隊在《Current Biology》(IF=8.1)發表了題為“Three RLKs integrate SHR-SCR and gibberellins to regulate root ground tissue patterning in A
230 次大腦通過 PGE2 骨內感受調節負重骨:踝關節骨性關節炎和疼痛的影響 2025-4-21
Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and painSubject terms: Bone, Pathogenesis內感受(Interoception)是一種監