39 次染色質(zhì)開(kāi)放性測(cè)序(ATAC-seq)原理以及應(yīng)用領(lǐng)域 2025-4-30
技術(shù)簡(jiǎn)介染色質(zhì)開(kāi)放性測(cè)序(Assay for Transposase-Accessible Chromatin using sequencing,ATAC-seq),一種用于檢測(cè)染色質(zhì)開(kāi)放性的高通量測(cè)序技術(shù),通過(guò)Tn5轉(zhuǎn)座酶切割并標(biāo)記開(kāi)放的染色質(zhì)區(qū)域
56 次ATAC-seq開(kāi)啟新視角:探索Shox2基因沙漠的神秘功能 2025-4-30
2024年7月,發(fā)表在《Nature Communications》的一篇文章“A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival”,聚焦Shox2基因
182 次機(jī)械拉伸誘導(dǎo)的活性氧驅(qū)動(dòng)新生豬腎上皮細(xì)胞內(nèi)皮素的產(chǎn)生 2025-4-27
Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cellsKeywords: Acute kidney injury; Endothelin; Endothelin
214 次Hes1/Piezo1 通路在糖皮質(zhì)激素誘導(dǎo)的骨質(zhì)疏松癥中的關(guān)鍵作用 2025-4-22
The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosisKeywords: Bone biology; Bone disease; Osteoporosis; Therapeutics.糖皮質(zhì)激素
329 次DAP-seq技術(shù)助力揭示擬南芥根基本組織發(fā)育的調(diào)控機(jī)制 2025-4-21
2024 年 11月 18 日,蘭州大學(xué)黎家教授團(tuán)隊(duì)在《Current Biology》(IF=8.1)發(fā)表了題為“Three RLKs integrate SHR-SCR and gibberellins to regulate root ground tissue patterning in A