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509 次 硫酸化K5多糖具有抑制腫瘤細胞增殖和轉移的潛力 2025-1-7
硫酸化K5多糖是一種經過硫酸化修飾的K5多糖。K5多糖是一種天然存在的多糖，主要來源于大腸桿菌（Escherichia coli）的K5莢膜多糖。K5多糖的結構與肝素（heparin）的前體物質非常相似，因此具有潛
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559 次 B細胞前體急性淋巴細胞白血病在骨髓間充質基質中引發干擾素α/β反應 2024-12-30
B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/β response in bone marrow-derived mesenchymal stromaKWS：BCP-ALL；interferon-α/β；bone m
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588 次 機械力經靶向 SMAD1促巨噬細胞外泌體 UCHL3促進骨髓間充質干細胞成骨 2024-12-30
Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1Keywords: Exosomes; Macrophages; Mechanical fo
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415 次 人牙齦成纖維細胞的成骨分化可抑制破骨細胞形成 2024-12-23
Osteogenic Differentiation of Human Gingival Fibroblasts Inhibits Osteoclast FormationKeywords: gingival fibroblasts; osteoblasts; osteoclastogenesis; osteoclasts; osteogenesis.牙齦
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453 次 循環牽張應力通過整合素αVβ3-肌動蛋白絲軸調控MSCs早期成骨分化 2024-12-23
Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stressKeywords: Integrin &
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1022 次 FAK 通過 Drp1 調控心肌細胞線粒體裂變和功能 2024-12-16
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1Keywords: Drp1; FAK; fibronectin; mitochondrial fission.線粒體對于心肌細胞的能量產生至關重要，其功能障礙與
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1233 次 機械應力經TGF-β1 激活 Smad2/3 并抑制 NF-κB 以防軟骨細胞焦亡 2024-12-16
Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthriti
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628 次 動脈粥樣硬化中血流紊亂會損害MerTK介導的主動脈內皮細胞的胞葬作用 2024-12-9
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosisKeywords: Disturbed flow; MerTK; RNA-seq; atherosclerosis; efferocytosis; prot
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615 次 機械敏感的多囊蛋白1促進骨膜干/祖細胞在骨折愈合中的骨軟骨分化 2024-12-9
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healingKeywords: Fracture healing; Mechanical stress; Peri
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572 次 TNFSF12/TWEAK調節結腸炎性成纖維細胞并促其與單核細胞相互作用 2024-12-2
The TNFSF12/TWEAK Modulates Colonic Inflammatory Fibroblast Differentiation and Promotes Fibroblast-Monocyte InteractionsKWS：TNFSF12/TWEAK；Colonic Inflammatory Fibroblast；Differ
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549 次 miR-342-5p通過抑制 MYC增強內皮細胞對剪切力的動脈化響應 2024-12-2
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYCKeywords: MT: Non-coding RNAs; Notch; arterialization; end
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718 次 激活的SIRT1 通過增強 H 型血管生成和骨形成的耦聯來促進骨修復 2024-11-25
SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesisKWS：SIRT1；bone repair；type H vessel formation；osteogenesis骨缺損可由感
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1040 次 血管內皮細胞機械敏感基因在動脈粥樣硬化形成和治療中的研究進展 2024-11-25
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosisKeywords: Atherosclerosis; Blood flow; Endothelial cell; M
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942 次 TFF切向流過濾系統在外泌體分離中的應用 2024-11-22
外泌體是直徑為30-150 nm的小細胞外囊泡。在生理和病理條件下，幾乎所有類型的細胞都可以釋放外泌體，在細胞通訊和表觀遺傳調控中發揮重要作用。外泌體天然存在于體液中，包括血液，唾液，尿液和
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658 次 CD97 在壓縮下通過 Rap1a/ERK 通路抑制破骨細胞分化 2024-11-18
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compressionSubject terms: Orthodontics, Cell signalling正畸治療是通過正畸牙齒移動（OTM）矯正咬合不正。OTM 是一種
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1687 次 Piezo1 介導的機械轉導導致血流紊亂誘導的動脈粥樣硬化內皮炎癥 2024-11-18
Piezo1‐Mediated Mechanotransduction Contributes to Disturbed Flow‐Induced Atherosclerotic Endothelial InflammationKeywords: Piezo1; atherosclerosis; endothelial cells; inflammati
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584 次 綠茶化合物EGCG在子癇前期的體外靜態和剪切應力模型中的抗氧化作用 2024-11-16
EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of PreeclampsiaKeywords: EGCG; NO; antioxidant; endotheli
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768 次 使用染料PHK 26進行體外細胞的標記和追蹤 2024-11-7
各類染料在實驗室中非常常用！本期我們將為大家介紹 PKH 26，一種用于體外細胞標記和追蹤的優質染料！ 讓我們結合實際案例，看看科研大佬們是如何利用 PKH 26 進行細胞研究的~本期要和大家分享的
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656 次 電壓門控性鈣通道α2δ亞基-1調控結腸癌進展并影響其微環境 2024-10-28
CACNA2D1 regulates the progression and influences the microenvironment of colon cancerKeywords: CACNA2D1; Colon cancer; Fibroblast; Voltage-gated calcium channel; p53.近年來，由于化
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580 次 人牙周膜間充質基質細胞通過旁分泌和細胞接觸介導對CD4+T的免疫調節 2024-10-28
Paracrine- and cell-contact-mediated immunomodulatory effects of human periodontal ligament-derived mesenchymal stromal cells on CD4+ T lymphocytesKeywords: CD4+ T lymphocytes; Co-
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