173 次揭秘TH17細胞分化“開關”:ChIP-seq 技術破解基因調控密碼 2025-4-27
2017年發表在Nature上的“Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation”的文章揭示了TGFβ的“反向調控”策略:正常
183 次機械拉伸誘導的活性氧驅動新生豬腎上皮細胞內皮素的產生 2025-4-27
Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cellsKeywords: Acute kidney injury; Endothelin; Endothelin
214 次Hes1/Piezo1 通路在糖皮質激素誘導的骨質疏松癥中的關鍵作用 2025-4-22
The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosisKeywords: Bone biology; Bone disease; Osteoporosis; Therapeutics.糖皮質激素
230 次大腦通過 PGE2 骨內感受調節負重骨:踝關節骨性關節炎和疼痛的影響 2025-4-21
Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and painSubject terms: Bone, Pathogenesis內感受(Interoception)是一種監
337 次骨肉瘤與巨噬細胞相互作用的IL-8經 FAK 促進瘤生長轉移 2025-4-8
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathwaySubject terms: Bone
353 次NETosis 驅動高血壓患者血壓升高和血管功能障礙 2025-4-7
NETosis Drives Blood Pressure Elevation and Vascular Dysfunction in HypertensionKeywords: extracellular traps; histones; hypertension; neutrophils; protein-arginine deiminase type
304 次微生理系統產生的剪切力可減少關節炎3D模型中TNF-α介導的軟骨損傷 2025-4-1
Microphysiological System-Generated Physiological Shear Forces Reduce TNF-α-Mediated Cartilage Damage in a 3D Model of ArthritisKeywords: TNF‐α; articular cartilage br
173 次Tenascin-X 介導血流誘導的 EndMT 和動脈粥樣硬化抑制 2025-3-25
Tenascin-X Mediates Flow-Induced Suppression of EndMT and AtherosclerosisKeywords: atherosclerosis; carotid arteries; endothelium; hemodynamics; inflammation; transforming growth f
267 次芥菜籽過敏原 Sina1 激活腸上皮細胞與樹突狀細胞 2025-3-24
Mustard seed major allergen Sin a1 activates intestinal epithelial cells and also dendritic cells that drive type 2 immune responsesKWS:Mustard seed;Sin a1;intestinal epithelial
158 次動脈粥樣硬化和內皮機械轉導 2025-3-17
Atherosclerosis and endothelial mechanotransduction: current knowledge and models for future researchKeywords: atherosclerosis; endothelial cell glycocalyx; mechanotransduction; sh
310 次HEG1 通過調節內皮細胞中KLF2/4 表達來預防動脈粥樣硬化 2025-3-17
HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial CellsKeywords: KLF2/4; atherosclerosis; endothelial cells; heart-of-glass 1